Over the past few centuries, yellow fever outbreaks have led to numerous cases and related fatalities. While the World Health Organization says most severe yellow fever (YF) cases have a fatality rate of around 39%, recent data from South America indicates an unfortunate increase in deaths.
Since 2024, the Republic of Colombia has faced an active YF outbreak. As of February 21, 2025, 40 cases have been confirmed (17 in 2025), with 19 related deaths, representing a case fatality rate (CFR) of 47%.
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