Lyme disease has been a nationally notifiable condition in the United States since 1991 without a U.S. Food and Drug Administration (FDA) approved vaccine.
Initially identified in Lyme, Connecticut, in 1976, over 63,000 cases of Lyme disease were reported by state health departments and the District of Columbia in 2022, primarily in the northeastern U.S.
However, based on the continued positive progress of an innovative multivalent protein subunit Lyme disease vaccine candidate, nature lovers may soon gain protection from this Black-legged tick-borne disease.
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