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In 2013, the World Health Organization (WHO) withdrew its recommendation for the yellow fever (YF) vaccine booster doses. However, new research supports the Brazilian National Immunization Program's recommendation for a booster dose of the vaccine at four years of age.
This vaccination policy change is vital for the Federative Republic of Brazil as it combats the spread of this severe mosquito-transmitted virus. 

In 2013, the World Health Organization (WHO) withdrew its recommendation for the yellow fever (YF) vaccine booster doses. However, new research supports the Brazilian National Immunization Program's recommendation for a booster dose of the vaccine at four years of age.
This vaccination policy change is vital for the Federative Republic of Brazil as it combats the spread of this severe mosquito-transmitted virus. 

In 2024, approximately 13 million dengue cases were reported, marking the highest year on record. Now classified as a grade 3 emergency, this mosquito-transmitted disease could cause additional outbreaks, endangering 4 billion people worldwide.
Therefore, access to innovative vaccines has become an essential public health priority in 2025.

Despite the availability of effective treatments and vaccines for certain types of meningitis, the disease continues to pose a significant global health threat.
According to the World Health Organization (WHO), various pathogens can cause meningitis, with approximately 2.5 million cases reported worldwide in 2019. This figure includes 1.6 million cases of bacterial meningitis, the most dangerous form, which led to around 240,000 deaths.