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100 Year Old Tuberculosis Vaccine Getting an Upgrade

In COVID-19, Latest News by Precision Vaccinations

After 100 years of use and billions of vaccinations, the world's deadliest infectious disease vaccine may soon be enhanced to meet the needs in 2025.
In a press release published on February 26, 2025, IAVI and Biofabri, a subsidiary of Zendal, announced that the first doses of tuberculosis MTBVAC vaccine candidate had been administered in the IMAGINE phase 2 clinical trial in Paarl, South Africa.

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Pre-Appointment Vaccine Information Boosts Uptake 16%

In COVID-19, Latest News by Precision Vaccinations

A recent study identified two proven, easy-to-implement tactics to increase vaccine uptake: Communicating doctor's or pharmacists' endorsements and delivering trusted vaccine information before an appointment. 
This University of Virginia School of Medicine study published by Open Forum Infectious Diseases concluded that strategies to engage older adult patients in vaccine decision-making increased rsv vaccination rates and patient-reported willingness to get vaccinated.

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Rotavirus Cases Spike in February 2025

In COVID-19, Latest News by Precision Vaccinations

Numerous health agencies have repeatedly stated that getting the rotavirus vaccine is the best way to protect against this 'stomach' disease. Rotavirus is the leading global cause of severe dehydrating diarrhea in children.
A recent study supports that recommendation, finding a sustained and substantial decline in rotavirus-coded acute gastroenteritis (AGE) hospitalizations in children and adolescents 13 years after introducing the rotavirus vaccine.

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Level 2 Travel Alert Issued for France's La Réunion Chikungunya Outbreak

In COVID-19, Latest News by Precision Vaccinations

While health agencies have issued travel alerts regarding France's Department of La Réunion Chikungunya outbreak for years, cases have spiked substantially since early 2025.
As of February 18, 2025, and since August 23, 2024, ARS Reunion confirmed 1,069 indigenous (local) cases recorded, including 927 since January 1, 2025.
The municipalities of Étang-Salé and Le Tampon have the most Chikungunya virus (CHIKV) cases, with 228 and 169 cases, respectively.

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Can Fractional Yellow Fever Vaccinations Decrease Deaths in the Americas

In COVID-19, Latest News by Precision Vaccinations

While the Yellow fever vaccine has been found highly effective when administered as a single dose, researchers have continued to examine the minimum dose requirements for seroconversion.
These researchers say the potential advantages of offering fractional doses are increased vaccinations and reduced under-vaccination, which have become a measurable health concern in the Region of the Americas over the past few years.
For example, 61 human cases of yellow fever were confirmed in the Region of the Americas in 2024, of which 30 were fatal (case fatality ratio, 50%).